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Sunday, 15 July 2018

Why DNA make some people rich and successful in life


              

Some individuals are very influential, powerful and rich their DNA play a vital role to achieve that, although DNA didn't determine overall riches among the human populace, but in one way or another being rich and successful is in the DNA.

Study involved 20,000 individuals from Britain, New Zealand, and the US 

Found men and women with ‘genes for education’ did better academically

However, the same genes also helped make someone upwardly socially mobile

Scientists have found social mobility is partially written into our genes, which can make us high-flyers or high-earners.
A study of more than 20,000 people in the UK, US and New Zealand found those with certain genetic variations earned more money, had better careers and got further in education.

Regardless of which class they came from, their genes could help them do better in life than their parents before them.

The study lends weight to the theory that nature rather than nurture largely determines how well people get on in their lives.

A team of researchers from Duke University School of Medicine in Durham, North Carolina, undertook a genome-wide association study (GWAS) on more than 20,000 individuals from Britain, New Zealand, and the United States who were followed from childhood into adulthood.

The GWAS looked for thousands of tiny changes in genetic code in the individuals that previous studies have linked with success at school.

Unsurprisingly, they found that men and women with ‘genes for education’ – or high polygenic scores – did better academically.

Those with a high polygenic score did better in terms of education, occupation, and wealth, compared with their parents and siblings, regardless of the individuals’ familial social class as children.

Lead author, Department of Population Health Sciences, Duke University Dr. Daniel Belsky, said: “Findings from these analyses show that education-linked genetics may provide clues to biological processes in human development that influence success in school, at work, and in the accumulation of wealth across life.”

The authors say our genes explain only roughly four per cent of differences in social mobility.

People with a high genetic score for education also tend to come from more affluent homes.

But even when parents’ social class is taken into account, the study found genes still have an effect.

A mother’s genetic score could even predict her child’s educational achievement, suggesting someone’s genes could even improve the success of the next generation by changing their own behaviour.

One explanation for the connection between education-linked genetics and social class is that a person’s education-linked genetics influence their development of traits and behaviours that, in turn, contribute to their success.

For example, education-linked genetics could influence brain development in ways that affect behaviour, leading to differences in achievement in school and beyond.


The latest study build earlier work by Duke University which found similar results on a smaller test group of 1,000 people in New Zealand.

Data available ranged from the age at which they said their first words to how much money they earn as adults.

As with the most recent study, Dr Belsky also studied their DNA, looking for 'success genes'.

As babies, individuals with 'success genes' started to speak earlier, as children they learned to read more quickly and by the age of 38, they had more prestigious jobs, earned more and travelled more.

They were also more friendly and likeable and had wealthier spouses.

Dr Belsky said: ‘It’s a “nice guys finish first” story that I didn’t expect to find.’

The genes also helped make individuals upwardly mobile.

However, despite their achievements, those with the ‘genes for education’ were no happier or healthier than other adults.

Writing in the journal Psychological Science, Dr Belsky said that the effect of the ‘genes for education’ on any one child’s life is small.

However, boosting their impact could have a huge impact on the population overall.

Future possibilities include tailoring children’s education to their genes.

Another, more controversial possibility, involves genetic screening of embryos, to give IVF patients babies with the greatest odds of growing up to be a success.


WHAT ARE POLYGENIC SCORES?
A polygenic score (polygenic means many genes) is an algorithm that looks at an individual's DNA.

It adds up multiple variants about an individual's health and social status.

Researchers say this number could indicate advantages inherited by some people in the form of biological mechanisms (genes) or socially transmitted opportunities (for example class) from their parents.

From this, researchers use it to predict future educational and economic success.

Research has shown that children with higher polygenic scores (PGSs) were more likely on average to obtain an A and B at GCSE.

They also found that 65 per cent of those with the higher PGS went on to do A-levels while only 35 per cent of those with lower scores did the same.

It can also be used to work out which people have a genetic risk for certain traits or diseases.

Some traits - for example whether an individual has cystic fibrosis - are based on just the presence or absence of a single variant.

However, the vast majority of traits - such as height to vitamin D levels - are based on many variants.

A PGS helps put one person's result in the context of the rest of the population.

Polygenic traits score directly or indirectly influences, health, intelligent, riches, poverty, lifestyle, failure and success. I believed that  Nature and Nature synchronize to create a pattern in anything we do in life.

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